Dibawah ini adalah informasi produk dari Combo Package Rota-Rod. Untuk diskusi produk bisa menghubungi kontak PT. Andaru Persada Mandiri via whatsapp 087777277740 atau telepon 0251-7504679.
The RotaRod is a simple test to assess motor function and coordination in rodents. Motor coordination or fatigue can be evaluated by measuring the time the animal stays on a rotating rod before falling. The Rod can rotate at constant, accelerating, rocking (back and forth) or through complex acceleration/deceleration ramps, thanks to the included PC software XPad.
Description Combo Package Rota-Rod
Background
The rotarod test, invented by Dunham and Miya (1957) and transformed into a science-grade device by Ugo Basile, is one of the oldest used in assessing the effects of a drug on animal behavior. Today it is obviously used in phenotyping and not only in drug screening.
Drugs (e.g. benzodiazepines) or specific phenotypes alter neuromuscular coordination and hence the time that the mouse or rat remains on the rotating rod.
Multiple animals can be tested at the same time and several protocols exist to train and assess the motory coordination through the falling time.
The output results include for each lane:
- Time elapsed
- Revolutions
- Distance
- Speed
- Rotating mode
System components and main features
The Ugo Basile Rotarod comes complete with:
- An electronic unit with touch screen to set all parameters and save data
- USB port to save data and export them in CSV files
- A PC software to build custom rotation ramps and populate your animal vivarium
Additional features include:
- TTL input/outputs for trip box status and start/stop of the test
- COM port for maintenance purposes
- Ethernet port for support and maintenance (to be used at the factory only)
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Features & Benefits Combo Package Rota-Rod
| Feature | Benefit |
| Constant, rocking, accelerating and complex accelerating ramps | Flexibility for performing virtually all types of motor function and coordination behavioral experiments |
| Mouse-Rat combination package | The same device cannot be used effectively (think of cleaning) or rats and mice without risk of confounding factors, so a highly discounted package is available for those that buy the two models. |
| Optional Rod enlarger | It allows to test different animal models and also to vary the test difficulty without acting on the speed or mode |
| Speed adjustable from 3 to 80 RPMs and multiple modes (constant, rocking, accelerating, complex accelerating ramps) | Allows for a very broad range of animal models and experimental settings |
| Control unit and USB key saving | No need to connect a PC |
| Automatic conversion of data into CSV files for the USB stick | Possibility to open files in Excel |
| PC software | Possibility to populate your vivarium of animals and to build complex temperature ramps |
Specification Combo Package Rota-Rod
|
General |
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| Commands | 4,3” touch-screen, usable with gloves | ||
| Read-out | Touch-screen and PC (via USB key) | ||
| Power Requirement | Universal input 100-240 VAC, 50-60Hz, 40W max. | ||
| Sound Level | |||
| Operating Temperature | 10° to 40° C | ||
| Trip Box | Stainless-steel to ease sterilization | ||
|
Dimensions |
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| Animal | Mice | Rats | Fat Rats |
| Lanes | 5 lanes for mice | 4 lanes for Rats | 4 lanes |
| Rod diameter | 3 cm | 6 cm | 8 cm |
| Rod Width | 5,8 cm | 8,7 cm | 12 cm |
| Fall Height | 16 cm | 30 cm | 40 cm |
|
Operation |
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| Speed | Adjustable from 3 to 80 RPM, in steps of 1 RPM (Custom ramp mode allows start from 0RPM) | ||
| Mode | Constant, ramp, reverse ramp, custom ramp and rocking | ||
| Start/Stop | From the touch-screen | ||
| Detection | Trip box magnetic sensor | ||
| Results | Time Elapsed, Revolutions, Distance, Speed, Mode for each lane | ||
| Data Acquisition | .csv exported file (via USB key) | ||
| Data Portability | By USB flash drive | ||
| TTL Output | Trip box status, rotating direction, start/stop experiment | ||
| Data Out | exported to .cvs | ||
| Data In | Import protocol and custom ramps | ||
|
Physical |
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| Total Weight | 11 Kg | 15 Kg | 17 Kg |
| Shipping Weight | 16 Kg | 21 Kg | 40 Kg |
| Dimensions | 46 x 28 x 33 cm | 55 x 46 x 57 cm | 70 x 46 x 65 cm |
| Packing Dimensions | 70 x 36 x 46 cm | 70 x 36 x 46 cm | 77 x 65 x 83 cm |
|
Warranty |
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| Warranty | Mouse Rotarod is covered by a 12 months warranty + 12 months upon product registration | ||
| UB-Care | Additional UB-Care can be added for additional 12 or 24 months | ||
Application Combo Package Rota-Rod
The RotaRod test is commonly used in combination with other motor tests, such as grip strength and hanging test to measure, motor function, coordination and balance.
The test starts with a training trial with the animals placed on the rod rotating at the lowest speed. A time threshold (e.g. 1 minute) is set, below which the animal is immediately put back on the RotaRod until it stays on the rod for the threshold time.
After training, the real trials start and the latency to fall as well as the other parameters (see above) are recorded.
The classic test was run at constant speed, but already in the ‘60s (Jones and Roberts, 1968), the advantages of using accelerating modes were shown, through training reduction, increased sensitivity and statistical significance.
The test is used to test motor deficits in the most common animal models of Parkinson’s, ALS, Huntington’s disease, multiple sclerosis, brain injury and many more.
Sumber informasi produk didapat dari website principle langsung pada tautan berikut : ugobasile
Demikian informasi produk Combo Package Rota-Rod. Bagi anda yang membutuhkan diskusi cepat produk ini bisa menghubungi contact PT. Andaru Persada Mandiri via whatsapp 087777277740 atau telepon 0251-7504679. Link alamat kami sertakan pada Google Maps.
